Rational tangle surgery and Xer recombination on catenanes
Darcy, Isabel K. · Ishihara, Kai · Medikonduri, Ram K. · Shimokawa, Koya
Original · EN
The protein recombinase can change the knot type of circular DNA. The action of a recombinase converting one knot into another knot is normally mathematically modeled by band surgery. Band surgeries on a 2-bridge knot N((4mn-1)/(2m)) yielding a (2,2k)-torus link are characterized. We apply this and other rational tangle surgery results to analyze Xer recombination on DNA catenanes using the tangle model for protein-bound DNA.
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