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arXiv 2007-04-19 DOI 10.1016/j.nimb.2008.02.025 0 views

Comparative study of depth-dose distributions for beams of light and heavy nuclei in tissue-like media

Pshenichnov, Igor · Mishustin, Igor · Greiner, Walter

Original · EN

We study the energy deposition by light and heavy nuclei in tissue-like media as used for cancer therapy. The depth-dose distributions for protons, ³He, ¹²C, ²⁰Ne, and ⁵⁸Ni nuclei are calculated within a Monte Carlo model based on the GEANT4 toolkit. These distributions are compared with each other and with available experimental data. It is demonstrated that nuclear fragmentation reactions essentially reduce the peak-to-plateau ratio of the dose profiles for deeply penetrating energetic ions heavier than ³He. On the other hand, all projectiles up to ²⁰Ne were found equally suitable for therapeutic use at low penetration depths.

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