Hydrodynamic and rheology of active polar filaments

Original · EN

The cytoskeleton provides eukaryotic cells with mechanical support and helps them perform their biological functions. It is a network of semiflexible polar protein filaments and many accessory proteins that bind to these filaments, regulate their assembly, link them to organelles and continuously remodel the network. Here we review recent theoretical work that aims to describe the cytoskeleton as a polar continuum driven out of equilibrium by internal chemical reactions. This work uses methods from soft condensed matter physics and has led to the formulation of a general framework for the description of the structure and rheology of active suspension of polar filaments and molecular motors.