Influence of progressive central hypovolemia on multifractal dimension of cardiac interbeat intervals

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We analyzed the heartbeat time series of 12 human subjects exposed to progressive central hypovolemia with lower body negative pressure. Two data processing techniques based on wavelet transforms were used to determine the change in the non-stationary nature of the time series with changing negative pressure. Our results suggest that autonomic neural mechanisms driving cardiac interbeat intervals during central hypovolemia go through various levels of multifractility.