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arXiv 1999-10-14 2 views

Stable integration of isolated cell membrane patches in a nanomachined aperture: a step towards a novel device for membrane physiology

Fertig, N. · Tilke, A. · Blick, R. H. · Kotthaus, J. P. · Behrends, J. C. · Bruggencate, G. ten

Original · EN

We investigate the microscopic contact of a cell/semiconductor hybrid. The semiconductor is nanostructured with the aim of single channel recording of ion channels in cell membranes. This approach will overcome many limitations of the classical patch-clamp technique. The integration of silicon-based devices 'on-chip' promises novel types of experiments on single ion channels.

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